Knee osteoarthritis is one of the most common musculoskeletal disorders worldwide. It results from a combination of mechanical and biological processes that disrupt the balance between the synthesis and degradation of cartilage, subchondral bone, and other joint structures. This imbalance leads to cartilage fissuring, erosion, and loss, as well as osteophyte formation and subchondral bone sclerosis. As life expectancy continues to increase, the prevalence of osteoarthritis is rising steadily, creating a growing burden on individuals and healthcare systems.

The rapid advancement of regenerative medicine, particularly the use of autologous adipose-derived stem cell therapy, is opening new possibilities for a modern, safe, and promising conservative treatment approach for patients with knee osteoarthritis. Potential benefits include:

Repairing, regenerating, and restoring damaged articular cartilage
Improving symptoms and joint function
Utilizing the patient’s own stem cells, thereby reducing the risk of immune reactions and rejection
Treatment Process

To ensure safety and effectiveness, Hai Phong International General Hospital follows a strict professional protocol:

Step 1: Comprehensive Assessment

Patients undergo a thorough medical examination and evaluation to determine their suitability for stem cell therapy.

Step 2: Autologous Fat Tissue Collection

Adipose tissue is harvested in a standard operating room environment, ensuring optimal safety and procedural quality.

Step 3: Stem Cell Processing

The collected tissue undergoes:

Stem cell isolation
Cell culture and activation
Storage and preservation
Quality control and validation

These procedures are performed in a certified Tissue Bank under strict sterile conditions with rigorous dosage and safety control measures.

Step 4: Ultrasound-Guided Stem Cell Injection

The processed stem cells are injected into the knee joint under ultrasound guidance in a dedicated joint injection procedure room.

Post-Procedure Care
Important Instructions After Stem Cell Injection
Keep the injection site clean and dry for at least 24 hours.
Possible Reactions
Pain at the injection site: Rest and use pain-relieving medication such as paracetamol if necessary. Contact your physician if the pain worsens.
Significant swelling, redness, or severe pain at the injection site, with or without fever: Contact your physician immediately for further evaluation.
Contact Information

MSc. Resident Physician Nguyen Viet Khanh
Phone: (+84) 397 934 138

MSc. Resident Physician Vu Thi Van Anh
Phone: (+84) 962 125 297